Modern paints are now formulated to be better for the environment with low-VOCs and less overspray, but in many ways they have gotten worse for the person spraying them. You don't want to breathing in activated urethane paints, and dust masks from the hardware store do nothing to keep the bad stuff out. Don't forget eye protection as well. Eastwood has you covered though with removable cartridge respirators and face masks affordable enough for the home paint project.
Eastwood also has head socks, and coveralls too. But that's not all, we also have the full forced clean air systems the pros use to paint all day long without being affected by fumes. As well as systems with paint guns and respirators fed by the same air compressor line... And when the time comes to install a full dedicated spray booth, Eastwood has those too.